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Home   COVID-19 treatment studies for Quercetin  COVID-19 treatment studies for Quercetin  C19 studies: Quercetin  Quercetin   Select treatmentSelect treatmentTreatmentsTreatments
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0 0.5 1 1.5 2+ Mortality 67% Improvement Relative Risk ICU admission 67% Hospitalization 67% Viral clearance 74% Viral clearance (b) 89% c19quercetin.com Di Pierro et al. NCT04861298 Quercetin RCT EARLY TREATMENT Favors quercetin Favors control
Di Pierro, 42 patient quercetin early treatment RCT: 74% improved viral clearance [p<0.0001] https://c19p.org/dipierro2
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Potential Clinical Benefits of Quercetin in the Early Stage of COVID-19: Results of a Second, Pilot, Randomized, Controlled and Open-Label Clinical Trial
Di Pierro et al., International Journal of General Medicine, doi:10.2147/IJGM.S318949, NCT04861298 (history)
24 Jun 2021    Source   PDF   Share   Tweet
RCT 42 outpatients in Pakistan, 21 treated with quercetin phytosome, showing faster viral clearance and lower symptom severity with treatment. Patients in the treatment group were younger (43 vs. 56).
risk of death, 66.7% lower, RR 0.33, p = 1.00, treatment 0 of 21 (0.0%), control 1 of 21 (4.8%), NNT 21, relative risk is not 0 because of continuity correction due to zero events (with reciprocal of the contrasting arm).
risk of ICU admission, 66.7% lower, RR 0.33, p = 1.00, treatment 0 of 21 (0.0%), control 1 of 21 (4.8%), NNT 21, relative risk is not 0 because of continuity correction due to zero events (with reciprocal of the contrasting arm).
risk of hospitalization, 66.7% lower, RR 0.33, p = 1.00, treatment 0 of 21 (0.0%), control 1 of 21 (4.8%), NNT 21, relative risk is not 0 because of continuity correction due to zero events (with reciprocal of the contrasting arm).
risk of no viral clearance, 73.7% lower, RR 0.26, p < 0.001, treatment 5 of 21 (23.8%), control 19 of 21 (90.5%), NNT 1.5, day 7.
risk of no viral clearance, 88.9% lower, RR 0.11, p = 0.11, treatment 0 of 21 (0.0%), control 4 of 21 (19.0%), NNT 5.2, relative risk is not 0 because of continuity correction due to zero events (with reciprocal of the contrasting arm), day 14.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
This study is excluded in the after exclusion results of meta analysis: randomization resulted in significant baseline differences that were not adjusted for.
Di Pierro et al., 24 Jun 2021, Randomized Controlled Trial, Pakistan, peer-reviewed, 12 authors, trial NCT04861298 (history).
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